East Asians have proteins specific to coronaviruses
The inhabitants of the region regularly experienced coronavirus epidemics, as a result of which their population formed a certain hereditary immunity.
Biologists from Australia and the United States have discovered proteins specific to coronaviruses in East Asians. The research results were published on the bioRxiv preprint server.
Using the method of counting protein generations, scientists have found that adaptation to coronavirus infections among the inhabitants of the region began 25 thousand years ago.
It is known that throughout evolutionary history, the composition of proteins in each human population changes. Since proteins physically interact with viruses that enter the body, after each viral epidemic, substances specific to a particular pathogen are retained in the proteome of the population.
Researchers from the University of Adelaide in Australia, the Australian National University and the University of Arizona in the United States studied the proteomes of 26 different populations of people from five continents and selected proteins that strongly interact with coronaviruses.
In East Asians, a unique set of 42 proteins specific to coronaviruses was found to act against this group of pathogens three times more active than other proteins.
The authors estimated the age of the most ancient proteins at 900 generations.
According to scientists, epidemics of coronavirus infections in this part of the world occurred regularly from 25 to five thousand years ago, as a result of which a certain hereditary immunity was formed in the population.
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