Nobel Prize in Chemistry 2022. Three scientists created a chemical “Lego”: what is the essence
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Two scientists from the USA and a scientist from Denmark divided 920 thousand dollars as a reward for having come up with a way to connect molecules like Lego bricks.
In 2022, the Nobel Prize in Chemistry was awarded to Caroline Bertozzi (this is the eighth woman in history to receive a prize in chemistry) and Barry Sharpless (this is the second prize in chemistry for this scientist) from the USA, and the Dane Morten Meldal. The Nobel Committee gave them the award for laying the groundwork and actively developing a functional form of chemistry called click chemistry. Scientists have come up with a new way to connect molecules together, writes the BBC.
The scientists' discovery is that they have come up with a method that allows molecules to simply and easily connect to each other, like Lego pieces. This method is used to create new methods of cancer treatment and direct influence on tumor cells.
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To understand what click chemistry is, and Sharpless coined this term back in 2011, imagine the details Lego constructor. Some parts have protrusions, while others have notches. When you connect these parts together, there is a click or click, as it sounds in English.
When two chemical partners are perfect for each other, they come into contact and bond easily. These are fast chemical reactions that do not create many unwanted by-products.
The groundbreaking discovery of Bertozzi, who is the pioneer of bioorthogonal chemistry associated with living cells, is that she made click chemistry work in these living cells. Her merit lies in the fact that scientists can create new types of biomolecules and chemicals that work safely inside the human body and thanks to this, cancer drugs get to the right place.
According to representatives of the Nobel Committee, the work of the Nobel laureates had a huge impact on science and has great potential for the further development of medicine . The committee also said that this year's winners, who created a scientific breakthrough, did everything necessary to keep things simple and make chemical reactions easy and simple.
Barry Sharpless, Caroline Bertozzi and Morten Meldal, together shared a prize fund of 920 thousand US dollars.
We remind you that the Nobel Prize in Physics 2022 was also awarded to three scientists from France, the USA and Austria for making important discoveries in the field of quantum mechanics.
Focus also wrote that the Nobel Prize in Physiology or Medicine 2022 was awarded to a Swedish scientist for his work with the genome of an ancient human relative, the Neanderthal.