Taking an antibiotic after sex greatly reduces the risk of STBBIs | AIDS: on the trail of a pandemic

0
207

Taking an antibiotic after sex greatly reduces the risk of STBBI | AIDS: on the trail of a pandemic

The drug was so effective that researchers stopped clinical trials earlier than expected.

Taking an antibiotic after unprotected sex can significantly reduce the risk of contracting three bacterial sexually transmitted and blood-borne infections (STBBIs) in high-risk people, shows a study that will be presented at the International AIDS Conference in Montreal.

This could lead to a change in clinical guidelines, said Steven Deeks, AIDS specialist at the AFP. #x27;University of California, San Francisco (UCSF), which was not involved in the study.

Taking doxycycline reduced rates of gonorrhea and chlamydia infections among men who have sex with men by more than 60%, and also appeared to be highly effective against syphilis, but there were not enough cases for these latest results to be statistically significant.

The drug was so effective that the researchers stopped clinical trials earlier than expected.

The publication of this study comes as infection rates for these diseases are on the rise, especially among men who have sex with men, among whom condom use has declined since the widespread use of condoms. PrEP (pre-exposure prophylaxis), an effective preventive treatment against infection with the AIDS virus, HIV.

A previous clinical trial conducted by French researchers had demonstrated the ;effectiveness of doxycycline as post-exposure prophylaxis (PEP) against syphilis and chlamydia, but not against gonorrhea.

This new study involved approximately 500 people, mostly men who have gay sex, in San Francisco and Seattle.

Some of these people were on PrEP against HIV, others were carriers of this virus.

Within each of these two groups, about two-thirds of the participants received doxycycline, while the rest did not. Follow-up was ensured by collecting the results every three months.

Treatment was given within three days after exposure and as long as necessary depending on the frequency of the intercourse.

Taking the antibiotic reduced the incidence of these infections by 62% in participants with HIV, and by 66% in those on PrEP.

Side effects were mild and participants generally adhered to the treatment diligently.

We now have two studies that support the use of doxycycline as a PEP in men who have sex with men, says lead author Annie Luetkemeyer , of UCSF, at a press conference.

I really believe that we need to think very seriously about rolling out [this treatment] and how to integrate it into the guidelines, in order to advise its use.

She pointed out, however, that the available data supported the use of this treatment in a targeted manner in groups at high risk of sexually transmitted infections, but not everyone.

Further studies should look at the impact of resistance of these STBBIs or other bacteria to antibiotics, the authors added, as well as the potentially disruptive consequences of these drugs on gut flora.

LEAVE A REPLY

Please enter your comment!
Please enter your name here